Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.65 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 7/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | KDM1A | O60341 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1073458 | 0.86 | AKR1C3 (0.55) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL15590483 | 0.86 | AKR1C3 (0.55) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL5217474 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL323823 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL1172743 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL8295172 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL4126470 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL323824 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL2034678 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 | |
| SCHEMBL5315326 | 0.84 | FFAR1 (0.70) | AKR1C3AKR1C1HDAC4FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415496-B2 | Biobased polyesters | Amyris, Inc. | 2013-04-09 | — | — | US | disclosed |
| US-8367859-B2 | Cyclohexane 1,4 carboxylates | Amyris, Inc. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367858-B2 | Terephthalic and trimellitic based acids and carboxylate derivatives thereof | Amyris, Inc. (US) | 2013-02-05 | — | — | US | disclosed |
| WO-2012082725-A1 | CONTINUOUS DEHYDROGENATION OF 1,4-CARBOXYLATE SUBSTITUTED CYCLOHEXENES | Amyris, Inc. (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012082727-A1 | BIOBASED POLYAMIDES | Amyris, Inc. (US) | 2012-06-21 | — | — | WO | disclosed |
| EP-2443083-A2 | CYCLOHEXENE 1,4-CARBOXYLATES | Amyris, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| US-20110288310-A1 | CYCLOHEXANE 1,4 CARBOXYLATES | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288311-A1 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288263-A1 | BIOBASED POLYESTERS | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110282078-A1 | CYCLOHEXENE 1,4 -CARBOXYLATES | DRATHS CORPORATION (US) | 2011-11-17 | — | — | US | disclosed |
| WO-2010148081-A2 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148063-A2 | CYCLOHEXENE 1,4-CARBOXYLATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148049-A2 | PREPARATION OF TRANS, TRANS MUCONIC ACID AND TRANS, TRANS MUCONATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148080-A2 | CYCLOHEXANE 1,4 CARBOXYLATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148070-A2 | BIOBASED POLYESTERS | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288310-A1 | CYCLOHEXANE 1,4 CARBOXYLATES | CNR2, CBR1, CCR4 | AKR1C3 195/4885AKR1C1 271/4885HDAC4 962/4885 |
| US-20110282078-A1 | CYCLOHEXENE 1,4 -CARBOXYLATES | CBR1, MCM4, CCR4 | AKR1C3 103/4885AKR1C1 147/4885HDAC4 1238/4885 |
| US-20110288311-A1 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | TRIM4, DDT, PICALM | AKR1C3 495/4885AKR1C1 598/4885HDAC4 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.