Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30524090 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TSHR | |
| SCHEMBL250143 | 0.80 | ALDH1A1 (0.62) | ALDH1A1TSHR | |
| SCHEMBL26332592 | 0.79 | ALDH1A1 (0.54) | ALDH1A1TSHR | |
| SCHEMBL2371999 | 0.77 | BCHE (0.60) | ALDH1A1TSHR | |
| SCHEMBL27409564 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TSHR | |
| SCHEMBL2634579 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TSHR | |
| SCHEMBL2064880 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHR | |
| SCHEMBL124981 | 0.75 | ALDH1A1 (0.67) | ALDH1A1TSHR | |
| SCHEMBL29437308 | 0.75 | ALDH1A1 (0.67) | ALDH1A1TSHR | |
| SCHEMBL6680911 | 0.75 | POLB (0.60) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140058106-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2014-02-27 | — | — | US | disclosed |
| US-20120316120-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-12-13 | — | — | US | disclosed |
| US-20120149900-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-06-14 | — | — | US | disclosed |
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2012-04-19 | — | — | US | disclosed |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149900-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | ALDH1A1 2452/4885TSHR 784/4885 |
| US-20140058106-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PFAS, ODC1, AOC1 | ALDH1A1 969/4885TSHR 1932/4885 |
| US-20120316120-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | ALDH1A1 2452/4885TSHR 784/4885 |
| US-20110054175-A1 | SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS | PFAS, ODC1, AOC1 | ALDH1A1 969/4885TSHR 1932/4885 |
| US-20120095217-A1 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | FLI1, CDC73, FOS | ALDH1A1 2452/4885TSHR 784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.