Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 13/20 | 0.88 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8195009 | 0.82 | NISCH (0.74) | NISCHLMNARECQLMAOAMAOB | |
| SCHEMBL8188355 | 0.81 | LMNA (0.92) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL523059 | 0.79 | LMNA (0.96) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8197880 | 0.78 | NISCH (0.69) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL5476725 | 0.77 | NISCH (0.79) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8201492 | 0.76 | NISCH (0.84) | NISCHLMNARECQLMAOBTOP2A | |
| SCHEMBL26126801 | 0.76 | NISCH (0.76) | NISCHLMNARECQLMAOAMAOB | |
| SCHEMBL771337 | 0.76 | NISCH (0.66) | NISCHLMNARECQLTOP2ATOP2B | |
| SCHEMBL8206164 | 0.75 | LMNA (0.68) | NISCHLMNARECQLMAOAMAOB | |
| SCHEMBL8198758 | 0.73 | NISCH (0.76) | NISCHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |