SCHEMBL670164

SCHEMBL670164

O=C(/N=C(/NC(=O)OCc1ccccc1)n1cccn1)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
ATM Q13315 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HTT P42858 1/20 0.38
MIF P14174 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL670165 1.00 POLB (0.43) POLBATMLMNASMN1; SMN2CA12
SCHEMBL5567091 1.00 POLB (0.43) POLBATMLMNASMN1; SMN2CA12
SCHEMBL22798569 0.92 POLB (0.44) POLBATMLMNASMN1; SMN2CA12
SCHEMBL8196306 0.92 POLB (0.44) POLBATMLMNASMN1; SMN2CA12
SCHEMBL6764378 0.89 SYK (0.41) POLBATMSMN1; SMN2NPC1RAB9A
SCHEMBL6764370 0.89 SYK (0.41) POLBCA12CA1
SCHEMBL6764374 0.89 SYK (0.41) POLBCA12CA1
SCHEMBL14271350 0.87 ALDH1A1 (0.40) POLBATM
SCHEMBL6624590 0.86 L3MBTL1 (0.39) SMN1; SMN2NPC1RAB9AHTT
SCHEMBL9254620 0.80 POLB (0.47) POLBLMNASMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US claimed
US-11427814-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2022-08-30 US claimed
US-20210214701-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2021-07-15 US claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP disclosed
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2025-11-18 US disclosed
US-20250102513-A1 KITS FOR ANALYSIS USING NUCLEIC ACID ENCODING AND/OR LABEL Encodia, Inc. (US) 2025-03-27 US disclosed
US-12122736-B2 Salty taste-enhancing agent and manufacturing method therefor, and salty taste-enhancing method NISSAN FOODS HOLDINGS CO., LTD. (JP) 2024-10-22 US disclosed
EP-3343225-B1 METHOD OF PREPARING SAMPLE FOR ANALYSIS AND ANALYSIS METHOD SHIMADZU CORP (JP) 2024-08-07 EP disclosed
WO-2024148174-A1 PEPTIDE SEQUENCER OREGON HEALTH & SCIENCE UNIVERSITY (US) 2024-07-11 WO disclosed
US-20240158829-A1 METHODS FOR BIOMOLECULE ANALYSIS EMPLOYING MULTI-COMPONENT DETECTION AGENT AND RELATED KITS DF PEPTIDE ACQUISITION LLC 2024-05-16 US disclosed
US-20240011009-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2024-01-11 US disclosed
EP-0944590-B1 AMINOGUANIDINES AND ALKOXYGUANIDINES AS PROTEASE INHIBITORS DIMENSIONAL PHARM INC (US) 2002-03-20 EP disclosed
EP-1179529-A1 NOVEL HYDROXAMIC ACID DERIVATIVES Daiichi Fine Chemical Co., Ltd. (JP) 2002-02-13 EP disclosed
US-6344486-B1 ANTICOAGULANTS 3-DIMENSIONAL PHARMACEUTICALS, INC. 2002-02-05 US disclosed
US-6344466-B2 ANTITHROMBOTIC ACTIVITY, USE IN INHIBITING LOSS OF BLOOD PLATELETS, INHIBITING FORMATION OF BLOOD PLATELET AGGREGATES, INHIBITING FORMATION OF FIBRIN, ANTICOAGULANTS 3-DIMENSIONAL PHARMACEUTICALS INC. 2002-02-05 US disclosed
US-20010037039-A1 Aminoguanidines and alkoxyguanidines as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-11-01 US disclosed
US-20010031870-A1 Benzamide and sulfonamide substitued aminoguanidines and alkoxyguanidines as protese inhibitors SOLL RICHARD M (US) 2001-10-18 US disclosed
US-6291514-B1 Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-09-18 US disclosed
US-6235778-B1 ANTICOAGULANTS 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-05-22 US disclosed
EP-0850950-A1 PEPTIDE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1998-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010037039-A1 Aminoguanidines and alkoxyguanidines as protease inhibitors F9, PLG, MMP9 POLB 2218/4885ATM 1682/4885LMNA 1787/4885
US-12122736-B2 Salty taste-enhancing agent and manufacturing method therefor, and salty taste-enhancing method TAS2R8, TAS2R13, TAS2R38 POLB 4632/4885ATM 3310/4885LMNA 4535/4885
US-20010031870-A1 Benzamide and sulfonamide substitued aminoguanidines and alkoxyguanidines as protese inhibitors PLG, F9, TFPI POLB 2279/4885ATM 2300/4885LMNA 1511/4885
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN POLB 73/4885ATM 3932/4885LMNA 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.