SCHEMBL670165

SCHEMBL670165

O=C(N=C(NC(=O)OCc1ccccc1)n1cccn1)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
ATM Q13315 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HTT P42858 1/20 0.38
MIF P14174 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5567091 1.00 POLB (0.43) POLBATMLMNASMN1; SMN2CA12
SCHEMBL670164 1.00 POLB (0.43) POLBATMLMNASMN1; SMN2CA12
SCHEMBL22798569 0.92 POLB (0.44) POLBATMLMNASMN1; SMN2CA12
SCHEMBL8196306 0.92 POLB (0.44) POLBATMLMNASMN1; SMN2CA12
SCHEMBL6764378 0.89 SYK (0.41) POLBATMSMN1; SMN2NPC1RAB9A
SCHEMBL6764370 0.89 SYK (0.41) POLBCA12CA1
SCHEMBL6764374 0.89 SYK (0.41) POLBCA12CA1
SCHEMBL14271350 0.87 ALDH1A1 (0.40) POLBATM
SCHEMBL6624590 0.86 L3MBTL1 (0.39) SMN1; SMN2NPC1RAB9AHTT
SCHEMBL9254620 0.80 POLB (0.47) POLBLMNASMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US claimed
US-11427814-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2022-08-30 US claimed
US-20210214701-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2021-07-15 US claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP disclosed
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2025-11-18 US disclosed
EP-4646595-A1 PEPTIDE SEQUENCER Oregon Health & Science University (US) 2025-11-12 EP disclosed
US-20250102513-A1 KITS FOR ANALYSIS USING NUCLEIC ACID ENCODING AND/OR LABEL Encodia, Inc. (US) 2025-03-27 US disclosed
US-12122736-B2 Salty taste-enhancing agent and manufacturing method therefor, and salty taste-enhancing method NISSAN FOODS HOLDINGS CO., LTD. (JP) 2024-10-22 US disclosed
EP-3343225-B1 METHOD OF PREPARING SAMPLE FOR ANALYSIS AND ANALYSIS METHOD SHIMADZU CORP (JP) 2024-08-07 EP disclosed
WO-2024148174-A1 PEPTIDE SEQUENCER OREGON HEALTH & SCIENCE UNIVERSITY (US) 2024-07-11 WO disclosed
US-20240158829-A1 METHODS FOR BIOMOLECULE ANALYSIS EMPLOYING MULTI-COMPONENT DETECTION AGENT AND RELATED KITS DF PEPTIDE ACQUISITION LLC 2024-05-16 US disclosed
US-6284914-B1 HYDROXAMIC ACID DERIVATIVES FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2001-09-04 US disclosed
US-6235778-B1 ANTICOAGULANTS 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-05-22 US disclosed
EP-1089973-A1 AMIDINO AND GUANIDINO AZETIDINONE TRYPTASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2001-04-11 EP disclosed
EP-1081132-A1 HYDROXAMIC ACID DERIVATIVES AND MEDICINAL UTILIZATION THEREOF Welfide Corporation (JP) 2001-03-07 EP disclosed
US-6147114-A HYDROXAMIC ACID DERIVATIVES FROM TUMOR NECROSIS FACTOR CONVERTING ENZYME FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2000-11-14 US disclosed
WO-1999067215-A1 AMIDINO AND GUANIDINO AZETIDINONE TRYPTASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-12-29 WO disclosed
US-5935932-A Bradykinin antagonists containing pentafluorophenylalanine UNIVERSITY TECHNOLOGY CORPORATION (US) 1999-08-10 US disclosed
EP-0850950-A1 PEPTIDE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1998-07-01 EP disclosed
EP-0832875-A1 HIGHLY WATER-SOLUBLE METALLOPROTEINASE INHIBITOR FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1998-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12122736-B2 Salty taste-enhancing agent and manufacturing method therefor, and salty taste-enhancing method TAS2R8, TAS2R13, TAS2R38 POLB 4632/4885ATM 3310/4885LMNA 4535/4885
US-12472267-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN POLB 73/4885ATM 3932/4885LMNA 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.