Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.45 |
| ▸ | MMP3 | P08254 | 12/20 | 0.45 |
| ▸ | MMP1 | P03956 | 7/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424487 | 0.86 | MMP2 (0.41) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8422729 | 0.81 | MMP2 (0.43) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8197789 | 0.81 | MMP2 (0.39) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL8198041 | 0.79 | MMP2 (0.39) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8422672 | 0.78 | GAA (0.39) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL8203109 | 0.77 | MMP2 (0.53) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8190215 | 0.76 | MMP1 (0.40) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7406988 | 0.75 | MMP1 (0.43) | MMP2MMP3MMP1MMP9MMP7 | |
| SCHEMBL27258950 | 0.74 | MMP2 (0.44) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8189876 | 0.74 | MMP1 (0.43) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740655-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-10-20 | — | — | EP | claimed |
| EP-0740655-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | claimed |
| WO-1995019961-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | claimed |
| US-6017889-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-01-25 | — | — | US | disclosed |
| EP-0740655-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-10-20 | — | — | EP | disclosed |
| EP-0740655-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019961-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |