Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.41 |
| ▸ | MMP3 | P08254 | 10/20 | 0.41 |
| ▸ | MMP1 | P03956 | 9/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197265 | 0.86 | MMP2 (0.45) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL8198159 | 0.82 | MMP1 (0.37) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL8422729 | 0.78 | MMP2 (0.43) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL8197789 | 0.68 | MMP2 (0.39) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL6435497 | 0.68 | MMP2 (0.38) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL7625425 | 0.68 | MMP3 (0.55) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL8189744 | 0.67 | MMP1 (0.40) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL8198041 | 0.66 | MMP2 (0.39) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL8197269 | 0.66 | MMP1 (0.42) | MMP2MMP3MMP1MMP13MMP9 | |
| SCHEMBL8197822 | 0.66 | MMP1 (0.42) | MMP2MMP3MMP1MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740655-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-10-20 | — | — | EP | claimed |