Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 13/20 | 0.37 |
| ▸ | MMP3 | P08254 | 8/20 | 0.37 |
| ▸ | MMP2 | P08253 | 5/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 4/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198210 | 0.85 | GAA (0.39) | GAAMMP1MMP3MMP2ACE | |
| SCHEMBL8200999 | 0.82 | MMP1 (0.36) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL8197789 | 0.81 | MMP2 (0.39) | MMP1MMP3MMP2ACEMMP13 | |
| SCHEMBL8198199 | 0.78 | ADAM17 (0.34) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL8197265 | 0.78 | MMP2 (0.45) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL8190215 | 0.76 | MMP1 (0.40) | MMP1MMP3MMP2ACEMMP13 | |
| SCHEMBL9010562 | 0.76 | ADAM17 (0.34) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL7406988 | 0.76 | MMP1 (0.43) | GAAMMP1MMP3MMP2MMP9 | |
| SCHEMBL7513209 | 0.75 | MMP1 (0.44) | MMP1MMP3MMP2MMP13MMP9 | |
| SCHEMBL9010548 | 0.75 | ADAM17 (0.33) | MMP1MMP3MMP2MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740655-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-10-20 | — | — | EP | claimed |