Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535902 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTTDP1HTTALDH1A1 | |
| SCHEMBL14689569 | 0.83 | MAPT (0.60) | SMN1; SMN2MAPTTDP1HTTACLY | |
| SCHEMBL28930303 | 0.81 | IGF2BP2 (0.41) | TDP1ALDH1A1ACLYHNF4AFOLH1 | |
| SCHEMBL6974190 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2PDCD1CD274ALDH1A1ACLY | |
| SCHEMBL4632581 | 0.79 | HNF4A (0.58) | SMN1; SMN2HTTALDH1A1HNF4AIKBKB | |
| SCHEMBL30394743 | 0.79 | HNF4A (0.58) | SMN1; SMN2HTTALDH1A1HNF4AIKBKB | |
| SCHEMBL28694563 | 0.78 | PKM (0.55) | SMN1; SMN2MAPTTDP1HTTALDH1A1 | |
| SCHEMBL8570517 | 0.78 | HTT (0.45) | MAPTPDCD1CD274HTTALDH1A1 | |
| SCHEMBL17799595 | 0.78 | HNF4A (0.56) | SMN1; SMN2HTTALDH1A1HNF4AIKBKB | |
| SCHEMBL28213739 | 0.78 | HTT (0.47) | SMN1; SMN2MAPTHTTALDH1A1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090817-A | Phenylpyridine derivatives useful as phosphodiesterase inhibitors | NOVARTIS AG (CH) | 2000-07-18 | — | — | US | disclosed |