Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574870 | 0.92 | LMNA (0.52) | CYP1A2CYP2C19CYP2D6LMNAHPGD | |
| SCHEMBL17766325 | 0.90 | RAB9A (0.52) | CYP1A2CYP2C19LMNAHPGDRAB9A | |
| SCHEMBL5263204 | 0.87 | NPC1 (0.50) | CYP1A2CYP2C19CYP2D6RAB9ANPC1 | |
| SCHEMBL17864829 | 0.86 | TSHR (0.50) | CYP1A2CYP2C19LMNAHPGDRAB9A | |
| SCHEMBL10242983 | 0.86 | TSHR (0.58) | CYP1A2CYP2C19CYP2D6LMNAHPGD | |
| SCHEMBL27645336 | 0.85 | RAB9A (0.48) | CYP1A2CYP2C19LMNAHPGDRAB9A | |
| SCHEMBL14270321 | 0.85 | MMP13 (0.49) | CYP1A2CYP2C19LMNAHPGDRAB9A | |
| SCHEMBL14499027 | 0.84 | RAB9A (0.47) | CYP1A2CYP2C19CYP2D6LMNAHPGD | |
| SCHEMBL30130796 | 0.84 | RAB9A (0.47) | CYP1A2CYP2C19LMNAHPGDRAB9A | |
| SCHEMBL3806762 | 0.83 | EPHX2 (0.56) | CYP1A2CYP2C19LMNARAB9AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097096-A2 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-109311882-A | adenine derivatives as protein kinase inhibitors | BCI制药公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-104884426-A | Cinnamide derivative | NIPPON ZOKI PHARMACEUCTICAL CO LTD | 2015-09-02 | — | — | CN | disclosed |
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |