SCHEMBL17864829

SCHEMBL17864829

CCCCOC(=O)NCc1cccc(CNC(=O)OC)c1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
EPHX2 P34913 2/20 0.49
SMN1; SMN2 Q16637 5/20 0.49
RAB9A P51151 4/20 0.49
HPGD P15428 2/20 0.49
LMNA P02545 2/20 0.49
FAAH O00519 2/20 0.48
NPC1 O15118 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
CASP1 P29466 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17766325 0.96 RAB9A (0.52) TSHREPHX2SMN1; SMN2RAB9AHPGD
SCHEMBL17549819 0.93 TSHR (0.54) TSHREPHX2SMN1; SMN2
SCHEMBL17754139 0.93 TSHR (0.54) TSHREPHX2SMN1; SMN2
SCHEMBL27645336 0.90 RAB9A (0.48) TSHREPHX2SMN1; SMN2RAB9AHPGD
SCHEMBL14499027 0.89 RAB9A (0.47) TSHREPHX2SMN1; SMN2RAB9AHPGD
SCHEMBL17342589 0.89 ALDH1A1 (0.50) TSHRSMN1; SMN2LMNA
SCHEMBL17863589 0.88 EPHX2 (0.49) TSHREPHX2SMN1; SMN2RAB9AHPGD
SCHEMBL14270321 0.87 MMP13 (0.49) TSHREPHX2SMN1; SMN2RAB9AHPGD
SCHEMBL26224788 0.87 RAB9A (0.45) TSHREPHX2SMN1; SMN2RAB9AHPGD
SCHEMBL18124428 0.86 TSHR (0.51) TSHREPHX2SMN1; SMN2HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device FUJIFILM CORPORATION (JP) 2019-10-29 US disclosed
US-10338277-B2 Polarizing plate protective film, polarizing plate, and display FUJIFILM CORPORATION (JP) 2019-07-02 US disclosed
US-10031264-B2 Polarizing plate and display device FUJIFILM CORPORATION (JP) 2018-07-24 US disclosed
US-9817156-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-11-14 US disclosed
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-9678249-B2 Polarizing plate protective film, polarizing plate and display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed
US-20160291210-A1 POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291213-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160291211-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-10-06 US disclosed
US-20160178809-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY FUJIFILM CORPORATION (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10457792-B2 Polarizing plate protective film, polarizing plate, and display device NBAS, SSB, GNA15 TSHR 1636/4885EPHX2 623/4885SMN1; SMN2 2279/4885
US-20170226317-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE NBAS, SSB, BIRC5 TSHR 1685/4885EPHX2 699/4885SMN1; SMN2 2393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.