Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2792610 | 0.75 | ALDH1A1 (0.34) | TMPRSS15ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL25410152 | 0.71 | TMPRSS15 (0.59) | TMPRSS15CYP1A2 | |
| SCHEMBL18674616 | 0.71 | RAB9A (0.41) | ALDH1A1HPGDKDM4EHSD17B10RAB9A | |
| SCHEMBL25408977 | 0.70 | TMPRSS15 (0.60) | TMPRSS15ALDH1A1HPGDRAB9A | |
| SCHEMBL24348890 | 0.69 | MAPK14 (0.55) | TMPRSS15ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL28745220 | 0.69 | DGAT1 (0.40) | ALDH1A1HPGDKDM4EHSD17B10DGAT1 | |
| SCHEMBL12410015 | 0.68 | ALDH1A1 (0.41) | ALDH1A1RAB9ASMN1; SMN2LMNACYP2C9 | |
| SCHEMBL27259611 | 0.68 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL17607366 | 0.68 | HCAR2 (0.47) | TMPRSS15ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL16332917 | 0.68 | HTR2C (0.40) | ALDH1A1HPGDKDM4EHSD17B10DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |