Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 8/20 | 0.49 |
| ▸ | MMP3 | P08254 | 8/20 | 0.49 |
| ▸ | MMP13 | P45452 | 6/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207218 | 0.87 | MMP1 (0.57) | MAPK1MMP1MMP3MMP13MMP2 | |
| SCHEMBL8207220 | 0.87 | MMP1 (0.57) | MAPK1MMP1MMP3MMP13MMP2 | |
| SCHEMBL8207216 | 0.87 | MMP1 (0.57) | MAPK1MMP1MMP3MMP13MMP2 | |
| SCHEMBL8210424 | 0.85 | TSHR (0.60) | TSHRMAPK1RECQLL3MBTL1BDKRB1 | |
| SCHEMBL8210472 | 0.84 | RAB9A (0.56) | TSHRMAPK1MMP1MMP3MMP13 | |
| SCHEMBL8212965 | 0.82 | TSHR (0.60) | TSHRMAPK1RECQLL3MBTL1BDKRB1 | |
| SCHEMBL8198983 | 0.80 | ALDH1A1 (0.62) | TSHRMAPK1RECQLL3MBTL1MMP1 | |
| SCHEMBL8238782 | 0.80 | MMP1 (0.49) | TSHRMAPK1RECQLL3MBTL1MMP1 | |
| SCHEMBL8238780 | 0.80 | MMP1 (0.49) | TSHRMAPK1RECQLL3MBTL1MMP1 | |
| SCHEMBL31086998 | 0.78 | MMP3 (0.72) | MMP1MMP3MMP13MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |