Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22931837 | 0.89 | KMT2A (0.58) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL3819098 | 0.86 | AKT1 (0.52) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL22361797 | 0.85 | AKT1 (0.50) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL6378857 | 0.85 | AKT1 (0.45) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL20341352 | 0.82 | AKT1 (0.49) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL357503 | 0.79 | AKT1 (0.47) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL9060170 | 0.77 | HDAC1 (0.60) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL23288368 | 0.76 | LMNA (0.60) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL10425083 | 0.76 | CTSK (0.44) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL1353124 | 0.75 | HDAC1 (0.50) | HDAC3HDAC1HDAC2NCOR2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |