Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737432 | 0.85 | AKT1 (0.42) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL10423904 | 0.85 | AKT1 (0.41) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL1737441 | 0.83 | HDAC3 (0.42) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL268899 | 0.83 | BCHE (0.43) | — | |
| SCHEMBL10423913 | 0.80 | AKT1 (0.42) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL10772982 | 0.79 | CTSK (0.39) | CTSK | |
| SCHEMBL3819098 | 0.79 | AKT1 (0.52) | HDAC3HDAC1HDAC2NCOR2AKT1 | |
| SCHEMBL8083713 | 0.79 | CTSK (0.43) | CTSK | |
| SCHEMBL15259724 | 0.76 | SLC15A1 (0.44) | — | |
| SCHEMBL8199047 | 0.76 | HDAC3 (0.49) | HDAC3HDAC1HDAC2NCOR2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918105-A | Novel compounds with collagenase-inhibiting activity, a process for their preparation and pharmaceutical compositions in which these compounds are present | SA LABORATOIRE ROGER BELLON (FR) | 1990-04-17 | — | — | US | disclosed |