Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207539 | 0.89 | PTGDR2 (0.35) | KDM4EGAAHTTSMN1; SMN2PTPN1 | |
| SCHEMBL8205725 | 0.85 | EIF4E (0.33) | GAASMN1; SMN2 | |
| SCHEMBL8209367 | 0.80 | GAA (0.39) | KDM4EGAAHTTSMN1; SMN2MEN1 | |
| SCHEMBL8199294 | 0.80 | GAA (0.35) | KDM4EGAAHTTSMN1; SMN2MEN1 | |
| SCHEMBL7703360 | 0.78 | CYP11B1 (0.40) | KDM4EMEN1KMT2A | |
| SCHEMBL8207364 | 0.76 | GAA (0.38) | NTRK1KDM4EGAAHTTSMN1; SMN2 | |
| SCHEMBL8271519 | 0.75 | SLC6A4 (0.37) | KDM4EGAAHTTSMN1; SMN2 | |
| SCHEMBL8212069 | 0.74 | FNTA (0.38) | — | |
| SCHEMBL8206760 | 0.73 | KDM4E (0.38) | KDM4EGAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL8206261 | 0.71 | FNTA (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |