Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 13/20 | 0.52 |
| ▸ | MMP1 | P03956 | 13/20 | 0.52 |
| ▸ | MMP7 | P09237 | 12/20 | 0.49 |
| ▸ | MMP13 | P45452 | 10/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211644 | 0.86 | HSD11B1 (0.52) | MMP3MMP1MMP7MMP13MMP2 | |
| SCHEMBL8212965 | 0.80 | TSHR (0.60) | TSHRMAPK1RECQLL3MBTL1MMP3 | |
| SCHEMBL8207986 | 0.77 | MMP3 (0.53) | TSHRMAPK1RECQLL3MBTL1MMP3 | |
| SCHEMBL7141901 | 0.76 | TSHR (0.58) | TSHRMAPK1RECQLL3MBTL1MMP3 | |
| SCHEMBL7141897 | 0.76 | TSHR (0.58) | TSHRMAPK1RECQLL3MBTL1MMP3 | |
| SCHEMBL8238782 | 0.73 | MMP1 (0.49) | TSHRMAPK1RECQLL3MBTL1MMP3 | |
| SCHEMBL8238780 | 0.73 | MMP1 (0.49) | TSHRMAPK1RECQLL3MBTL1MMP3 | |
| SCHEMBL5723530 | 0.72 | MMP1 (0.58) | MMP3MMP1MMP7MMP13MMP2 | |
| SCHEMBL7142447 | 0.72 | MMP3 (0.51) | MMP3MMP1MMP7MMP13MMP2 | |
| SCHEMBL23630430 | 0.72 | MMP3 (0.64) | MMP3MMP1MMP7MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |