Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836695 | 0.72 | POLB (0.51) | IDO1MAPTLMNAKMT2ARAB9A | |
| SCHEMBL37463 | 0.72 | IDO1 (0.70) | IDO1MAPTAKR1C3RAB9ANPSR1 | |
| SCHEMBL28385446 | 0.71 | IDO1 (0.56) | IDO1MAPTLMNAKMT2AAKR1C3 | |
| SCHEMBL8824655 | 0.70 | MAPT (0.52) | IDO1MAPTKMT2A | |
| SCHEMBL8199825 | 0.69 | IDO1 (0.43) | IDO1MAPTLMNAKMT2AAKR1C3 | |
| SCHEMBL11441117 | 0.69 | IDO1 (0.61) | IDO1MAPTLMNAKMT2AAKR1C3 | |
| SCHEMBL19621588 | 0.69 | IDO1 (0.61) | IDO1MAPTLMNAKMT2AAKR1C3 | |
| SCHEMBL6395926 | 0.69 | IDO1 (0.53) | IDO1MAPTLMNAAKR1C3RAB9A | |
| SCHEMBL11777064 | 0.69 | CA2 (0.51) | MAPTLMNAKMT2A | |
| SCHEMBL15559316 | 0.68 | MGLL (0.46) | MAPTKMT2ARAB9ANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026195-A1 | NOVEL AMINO ACID HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 2000-05-11 | — | — | WO | disclosed |