Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200375 | 0.94 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8199938 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8207755 | 0.92 | GRIN2C (0.48) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8210397 | 0.91 | KDM4E (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8212434 | 0.90 | SMN1; SMN2 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8198895 | 0.89 | SMN1; SMN2 (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8206045 | 0.85 | GRIN2C (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8200017 | 0.85 | MAPT (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8212479 | 0.83 | MAPT (0.38) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8200330 | 0.83 | MAPT (0.45) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |