Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 10/20 | 0.38 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206226 | 0.96 | ALDH1A1 (0.42) | GRIN2CALDH1A1KDM4EHPGDPLK1 | |
| SCHEMBL8199938 | 0.93 | ALDH1A1 (0.38) | GRIN2CALDH1A1KDM4EHPGDTRPV1 | |
| SCHEMBL8207755 | 0.92 | GRIN2C (0.48) | GRIN2CALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8200375 | 0.89 | ALDH1A1 (0.41) | GRIN2CALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8200315 | 0.84 | ALOX15 (0.40) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL8210397 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2HTT | |
| SCHEMBL8212434 | 0.80 | SMN1; SMN2 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2HTT | |
| SCHEMBL8212891 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL8198895 | 0.79 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2HTT | |
| SCHEMBL8200330 | 0.78 | MAPT (0.45) | GRIN2CALDH1A1KDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |