Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663872 | 0.82 | EGFR (0.39) | FFAR1ALOX5PTGS1PTGS2 | |
| SCHEMBL28814202 | 0.79 | GABRA1 (0.40) | GABRA1GABRB2FFAR1ALDH1A1NPC1 | |
| SCHEMBL28814204 | 0.79 | GABRA1 (0.40) | GABRA1GABRB2FFAR1ALDH1A1NPC1 | |
| SCHEMBL4190600 | 0.77 | ALOX5 (0.58) | ALOX5PTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL1122668 | 0.77 | ALOX5 (0.58) | ALOX5PTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL12237058 | 0.72 | ALDH1A1 (0.53) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL17260566 | 0.71 | ALDH1A1 (0.56) | GABRA1GABRB2PTGS2ALDH1A1HPGD | |
| SCHEMBL12237075 | 0.71 | SLC6A2 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12237077 | 0.70 | POLB (0.50) | ALDH1A1NPC1RAB9A | |
| SCHEMBL12237067 | 0.70 | PARP1 (0.44) | ALDH1A1HPGDSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2800470-A1 | SKIN LIGHTENING COMPOSITIONS | Merz North America, Inc. (US) | 2014-11-12 | — | — | EP | disclosed |
| WO-2013103874-A1 | SKIN LIGHTENING COMPOSITIONS | LASYA, INC. (US) | 2013-07-11 | — | — | WO | disclosed |
| US-6068834-A | ORALLY ADMINISTERING A MELANINS REDUCING OXY PHENOL COMPOUND TO THE MAMMAL FOR LIGHTENING THE MAMMALIAN SKIN; TYROSINASE INHIBITOR | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-30 | — | — | US | disclosed |