SCHEMBL4190600

SCHEMBL4190600

C#CC[C@H](C)CC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.58
PTGS1 P23219 3/20 0.58
PTGS2 P35354 3/20 0.58
LMNA P02545 1/20 0.43
RECQL P46063 1/20 0.43
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
F2R P25116 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
NPSR1 Q6W5P4 1/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
CA2 P00918 2/20 0.37
CA1 P00915 1/20 0.37
GAA P10253 2/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1122668 1.00 ALOX5 (0.58) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL7703814 0.80 ALOX5 (0.69) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL27983337 0.79 LMNA (0.49) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL27983336 0.79 LMNA (0.49) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL8200544 0.77 GABRA1 (0.38) ALOX5PTGS1PTGS2SMN1; SMN2ALDH1A1
SCHEMBL7701417 0.76 ALOX5 (0.83) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL10549570 0.74 ALOX5 (0.55) ALOX5PTGS1PTGS2LMNARECQL
Tebufelone SCHEMBL43674 0.74 PTGS2 (1.00) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL7702200 0.74 ALOX5 (0.61) ALOX5PTGS1PTGS2LMNARECQL
SCHEMBL7704543 0.73 ALOX5 (0.55) ALOX5PTGS1PTGS2LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218437-B1 ADMINISTERING A THERAPEUTIC AMOUNT OF DI-TERT-BUTYLPHENOL DERIVATIVE TO SUBJECT UNDER CONDITIONS SUCH THAT SAID SYMPTOMS ARE DIMINISHED THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2001-04-17 US claimed
EP-0496433-B1 Photoprotection compositions comprising chelating agents PROCTER & GAMBLE (US) 1999-03-24 EP claimed
US-5804572-A APPLYING SALICYLIC ACID, AND AN ANTIINFLAMMTORY AGENT WITH A CARRIER THE PROCTER & GAMBLE COMPANY (US) 1998-09-08 US claimed
US-5709847-A TOPICAL APPLICATION TO PREVENT DAMAGE TO SKIN BY ACCUTE ORCHRONIC UV EXPOSURE THE PROCTER & GAMBLE COMPANY (US) 1998-01-20 US claimed
US-5384115-A Photoprotection compositions comprising a radical scavenging compound and an anti-inflammatory agent THE PROCTER & GAMBLE COMPANY (US) 1995-01-24 US claimed
EP-0313303-B1 Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent PROCTER & GAMBLE (US) 1994-04-27 EP claimed
US-4954332-A TOPICAL SUNSCREEN AGENTS; ULTRAVIOLET RADIATION AND OXIDATION RESISTNCE THE PROCTER & GAMBLE COMPANY (US) 1990-09-04 US claimed
US-4946671-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1990-08-07 US claimed
US-4847069-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US claimed
US-4847071-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US claimed
US-4708966-A SUBSTITUTED DI-TERT-BUTYL PHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1987-11-24 US claimed
EP-3393410-B1 CUSTOMISABLE STOMA INSERT TAN JASON JIT SUN (AU) 2024-03-20 EP disclosed
US-11826277-B2 Customizable stoma insert TAN JASON JIT SUN (AU) 2023-11-28 US disclosed
US-20220117772-A1 CUSTOMIZABLE STOMA INSERT TAN JASON JIT SUN (AU) 2022-04-21 US disclosed
US-11207205-B2 Customisable stoma insert Tan, Jason Jit-sun (AU) 2021-12-28 US disclosed
US-4869897-A SUNCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-09-26 US disclosed
US-4847069-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US disclosed
US-4847072-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US disclosed
US-4847071-A SUNSCREEN AGENTS THE PROCTER & GAMBLE COMPANY (US) 1989-07-11 US disclosed
US-4708966-A SUBSTITUTED DI-TERT-BUTYL PHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 1987-11-24 US disclosed