Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196333 | 1.00 | ADRB2 (0.36) | ADRB2ADRB1ADRB3HTTHTR1A | |
| SCHEMBL7982471 | 0.90 | SLC6A2 (0.37) | ADRB2ADRB1ADRB3SIGMAR1NAMPT | |
| SCHEMBL7982467 | 0.90 | SLC6A2 (0.37) | ADRB2ADRB1ADRB3SIGMAR1NAMPT | |
| SCHEMBL7979656 | 0.88 | HTR1A (0.42) | ADRB2ADRB1ADRB3HTTHTR1A | |
| SCHEMBL7979658 | 0.88 | HTR1A (0.42) | ADRB2ADRB1ADRB3HTTHTR1A | |
| SCHEMBL8195910 | 0.86 | HRH4 (0.36) | ADRB2ADRB1ADRB3HTTHTR1A | |
| SCHEMBL8195916 | 0.86 | HRH4 (0.36) | ADRB2ADRB1ADRB3HTTHTR1A | |
| SCHEMBL7977997 | 0.81 | LATS1 (0.37) | HRH4IMPDH2NAMPTLMNA | |
| SCHEMBL7978001 | 0.81 | LATS1 (0.37) | HRH4IMPDH2NAMPTLMNA | |
| SCHEMBL8200604 | 0.79 | NAMPT (0.35) | ADRB2ADRB1ADRB3HRH4IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |