SCHEMBL8200618

SCHEMBL8200618

NCCOc1cc(F)cc(F)c1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.48
LTA4H P09960 2/20 0.42
PLA2G2A P14555 1/20 0.42
SOD1 P00441 1/20 0.40
IDO1 P14902 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ESR1 P03372 1/20 0.37
CYP19A1 P11511 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1290769 0.98 TAAR1 (0.46) TAAR1LTA4HPLA2G2ASOD1IDO1
SCHEMBL13411802 0.82 TAAR1 (0.59) TAAR1LTA4HPLA2G2AKDM4EESR1
SCHEMBL23067933 0.81 TAAR1 (0.48) TAAR1LTA4HPLA2G2AKDM4EESR1
SCHEMBL1239738 0.79 TAAR1 (0.57) TAAR1LTA4HPLA2G2A
SCHEMBL13731094 0.78 LOX (0.39) TAAR1
Hydrochloric Acid SCHEMBL1623693 0.77 TAAR1 (0.55) TAAR1LTA4HPLA2G2AKDM4E
SCHEMBL3922161 0.76 ALDH1A1 (0.48) SOD1
SCHEMBL5314766 0.76 SOD1 (0.40) SOD1IDO1
SCHEMBL4023626 0.76 SOD1 (0.40) SOD1IDO1
SCHEMBL6793710 0.76 KAT6A (0.43) LTA4HSOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US claimed
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2024-02-13 US claimed
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO RAD LABORATORIES INC (US) 2025-11-13 US disclosed
US-12390463-B2 Dosage forms and regimens for amino acid compounds PLIANT THERAPEUTICS, INC. (US) 2025-08-19 US disclosed
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins BIO-RAD LABORATORIES, INC. (US) 2025-07-22 US disclosed
US-20250223288-A1 AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. 2025-07-10 US disclosed
EP-4520329-A2 TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS Pliant Therapeutics, Inc. (US) 2025-03-12 EP disclosed
EP-4509512-A2 AMINO ACID COMPOUNDS AND METHODS OF USE Pliant Therapeutics, Inc. (US) 2025-02-19 EP disclosed
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS BIO-RAD LABORATORIES, INC. 2024-08-08 US disclosed
CN-118401521-A Integrin inhibitors and their use in combination with other agents 普利安特治疗公司 2024-07-26 CN disclosed
EP-4329755-A1 EXPANDED DOSAGE REGIMENS FOR INTEGRIN INHIBITORS Pliant Therapeutics, Inc. (US) 2024-03-06 EP disclosed
US-20200352942-A1 DOSAGE FORMS AND REGIMENS FOR AMINO ACID COMPOUNDS PLIANT THERAPEUTICS, INC. 2020-11-12 US disclosed
WO-2020210404-A1 DOSAGE FORMS AND REGIMENS FOR AMINO ACID COMPOUNDS PLIANT THERAPEUTICS, INC. (US) 2020-10-15 WO disclosed
US-10793564-B2 Amino acid compounds and methods of use PLIANT THERAPEUTICS, INC. (US) 2020-10-06 US disclosed
WO-2019244066-A2 PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION VIIV Healthcare UK (No.5) Limited (GB) 2019-12-26 WO disclosed
WO-2019244066-A2 PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION VIIV Healthcare UK (No.5) Limited (GB) 2019-12-26 WO disclosed
WO-2019173653-A1 AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. (US) 2019-09-12 WO disclosed
US-20190276449-A1 AMINO ACID COMPOUNDS AND METHODS OF USE PLIANT THERAPEUTICS, INC. 2019-09-12 US disclosed
WO-2012045729-A1 IMIDAZO [1, 2 -A] PYRIDINE AND PYRAZOLO [1, 5 -A] PYRIDINE DERIVATIVES AS TRPV1 ANTAGONISTS GLAXO GROUP LIMITED (GB) 2012-04-12 WO disclosed
WO-2000078737-A2 ARYLOXY ETHYLAMINO TRIAZINES AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345785-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 TAAR1 2870/4885LTA4H 1364/4885PLA2G2A 1166/4885
US-12364978-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 TAAR1 2870/4885LTA4H 1364/4885PLA2G2A 1166/4885
US-12390463-B2 Dosage forms and regimens for amino acid compounds ITGB6, ITGA6, ITGAV TAAR1 2684/4885LTA4H 2145/4885PLA2G2A 4534/4885
US-20240261775-A1 ANIONIC EXCHANGE-HYDROPHOBIC MIXED MODE CHROMATOGRAPHY RESINS ABCG2, SLC7A1, MSR1 TAAR1 2870/4885LTA4H 1364/4885PLA2G2A 1166/4885
US-20250223288-A1 AMINO ACID COMPOUNDS AND METHODS OF USE ITGB6, ITGA6, ITGA5 TAAR1 2658/4885LTA4H 1761/4885PLA2G2A 3878/4885
US-11896969-B2 Anionic exchange-hydrophobic mixed mode chromatography resins ABCG2, SLC7A1, MSR1 TAAR1 2870/4885LTA4H 1364/4885PLA2G2A 1166/4885
US-10793564-B2 Amino acid compounds and methods of use ITGB6, ITGA6, ITGA5 TAAR1 2658/4885LTA4H 1761/4885PLA2G2A 3878/4885
US-20190276449-A1 AMINO ACID COMPOUNDS AND METHODS OF USE ITGB6, ITGA6, ITGA5 TAAR1 2658/4885LTA4H 1761/4885PLA2G2A 3878/4885
US-20200352942-A1 DOSAGE FORMS AND REGIMENS FOR AMINO ACID COMPOUNDS ITGB6, ITGA6, ITGAV TAAR1 2684/4885LTA4H 2145/4885PLA2G2A 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.