Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412224 | 0.95 | CALM1 (0.51) | CALM1IGF1RALOX15ALOX5TAAR1 | |
| SCHEMBL11418258 | 0.90 | CALM1 (0.47) | CALM1IGF1RALOX15ALOX5TAAR1 | |
| SCHEMBL11414017 | 0.89 | CALM1 (0.46) | CALM1IGF1RALOX15ALOX5TAAR1 | |
| SCHEMBL11413062 | 0.89 | CALM1 (0.46) | CALM1IGF1RALOX15ALOX5TAAR1 | |
| SCHEMBL11412752 | 0.89 | LMNA (0.47) | CALM1IGF1RALOX15ALOX5TAAR1 | |
| SCHEMBL1845479 | 0.88 | TAAR1 (0.50) | CALM1TAAR1MIFF2RL1 | |
| SCHEMBL331162 | 0.86 | MIF (0.52) | MIF | |
| SCHEMBL17274310 | 0.82 | NAAA (0.63) | CALM1IGF1RALOX15TAAR1MIF | |
| SCHEMBL9427222 | 0.81 | MIF (0.44) | IGF1RALOX15TAAR1MIFSCN5A | |
| SCHEMBL330828 | 0.80 | MIF (0.50) | MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040289-A | ACTIVE DRUG TREATING OBESITY | DR. KARL THOMAE GMBH (DE) | 2000-03-21 | — | — | US | disclosed |