SCHEMBL330828

SCHEMBL330828

O=C=NCCCc1ccc(CCCN=C=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 7/20 0.50
NAAA Q02083 4/20 0.42
HTR3A P46098 2/20 0.38
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TRPA1 O75762 1/20 0.34
CYP2E1 P05181 1/20 0.34
CYP2A6 P11509 1/20 0.34
HIF1A Q16665 1/20 0.34
CYP2A13 Q16696 1/20 0.34
EPAS1 Q99814 1/20 0.34
FFAR1 O14842 1/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331162 0.93 MIF (0.52) MIFNAAACYP3A4TSHRHIF1A
SCHEMBL23124322 0.90 MIF (0.43) MIFNAAAFFAR1MAOB
SCHEMBL17117229 0.90 MIF (0.52) MIFNAAAHTR3AHTR3EHTR3B
SCHEMBL1149239 0.89 MIF (0.66) MIFNAAAHTR3ATRPA1CYP2E1
SCHEMBL11764558 0.88 CYP3A4 (0.57) MIFNAAAHTR3ACYP3A4TSHR
SCHEMBL10998392 0.86 MIF (0.41) MIFNAAA
SCHEMBL3591087 0.86 MIF (0.43) MIFNAAAHTR3A
SCHEMBL331135 0.85 MIF (0.48) MIFNAAAHTR3ACYP3A4TSHR
SCHEMBL11412224 0.85 CALM1 (0.51) MIFMAOB
SCHEMBL9358002 0.85 FFAR1 (0.44) MIFCYP3A4FFAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11267953-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2022-03-08 US claimed
US-20200123345-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2020-04-23 US claimed
US-10544283-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2020-01-28 US claimed
US-20180037722-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2018-02-08 US claimed
EP-3269749-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER Hoya Lens Thailand Ltd. (TH) 2018-01-17 EP claimed
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
US-12590232-B2 Multi-region foldable adhesive film and fabrication method therefor XINMEI FONTANA HOLDING (HONG KONG) LIMITED (CN) 2026-03-31 US disclosed
US-20260071091-A1 SELF-HEALING TRANSPARENT COATING COMPOSITION USING SUNLIGHT AND APPLICATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-03-12 US disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 EP disclosed
US-12503575-B2 Fine hollow particles comprising melamine-based resin KAGOSHIMA UNIVERSITY (JP) 2025-12-23 US disclosed
EP-3786154-B1 PREPARATION METHOD FOR POLYTHIOL HAVING IMPROVED STORAGE STABILITY SK PUCORE CO LTD (KR) 2025-08-20 EP disclosed
US-12384124-B2 Method for producing polarizing lens, polarizing film and polarizing lens HOYA LENS THAILAND LTD. (TH) 2025-08-12 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071091-A1 SELF-HEALING TRANSPARENT COATING COMPOSITION USING SUNLIGHT AND APPLICATION THEREOF PCNA, CUTA, COL1A1 MIF 374/4885NAAA 1787/4885HTR3A 2475/4885
US-12590232-B2 Multi-region foldable adhesive film and fabrication method therefor CDH1, SMCHD1, VCL MIF 537/4885NAAA 4579/4885HTR3A 423/4885
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 MIF 1569/4885NAAA 2866/4885HTR3A 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.