Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8203967 | 0.82 | CYP2D6 (0.35) | ALDH1A1ALOX15HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL8192460 | 0.71 | PTGS2 (0.40) | ALDH1A1HSD17B10SMN1; SMN2MAPTRAB9A | |
| SCHEMBL14188099 | 0.66 | ALDH1A1 (0.52) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL346292 | 0.62 | ALDH1A1 (0.61) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL124209 | 0.61 | ALDH1A1 (0.79) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL11547412 | 0.61 | ALDH1A1 (0.79) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2861214 | 0.61 | ALDH1A1 (0.58) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL17678529 | 0.60 | ALDH1A1 (0.50) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL13377111 | 0.60 | MAPT (0.45) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 | |
| Hypochlorous Acid SCHEMBL31412000 | 0.60 | ALDH1A1 (0.65) | ALDH1A1TSHRALOX15HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140344-A | FOR TREATING PATHOLOGICAL CONDITIONS SUCH AS ASTHMA, RHINITIS, ECZEMA AND PARASITIC INFECTIONS FEATURING TISSUE EOSINOPHILIA | SYNTEX (U.S.A.) INC. (US) | 2000-10-31 | — | — | US | disclosed |