Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200749 | 0.82 | ALDH1A1 (0.34) | HPGDALOX15HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8193166 | 0.79 | CYP3A4 (0.39) | HPGDKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL8192460 | 0.74 | PTGS2 (0.40) | HSD17B10KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL8201027 | 0.71 | DYRK1A (0.39) | CYP2D6CYP2C9CYP2C19KDM4EMAPT | |
| SCHEMBL5887443 | 0.68 | ACHE (0.46) | HPGDNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5887404 | 0.68 | L3MBTL1 (0.40) | HPGDESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL6047589 | 0.65 | PTGS1 (0.35) | NPC1RAB9ASMN1; SMN2PTGS2 | |
| SCHEMBL1132573 | 0.61 | KIF11 (0.45) | HPGDKDM4ENPC1MAPTRAB9A | |
| SCHEMBL9876351 | 0.61 | LMNA (0.46) | HPGDKDM4ENPC1MAPTRAB9A | |
| Iodide SCHEMBL28367770 | 0.60 | KIF11 (0.44) | HPGDKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140344-A | FOR TREATING PATHOLOGICAL CONDITIONS SUCH AS ASTHMA, RHINITIS, ECZEMA AND PARASITIC INFECTIONS FEATURING TISSUE EOSINOPHILIA | SYNTEX (U.S.A.) INC. (US) | 2000-10-31 | — | — | US | disclosed |