Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183272 | 0.72 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1HSD17B10TDP1 | |
| SCHEMBL14585671 | 0.69 | ADRA2A (0.36) | ALDH1A1KMT2AMEN1HSD17B10POLB | |
| SCHEMBL688353 | 0.67 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1HSD17B10TDP1 | |
| SCHEMBL2988135 | 0.66 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1HSD17B10TDP1 | |
| SCHEMBL30174280 | 0.66 | IKBKB (0.43) | ALDH1A1KMT2AMEN1HSD17B10TDP1 | |
| SCHEMBL4086271 | 0.65 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1HSD17B10POLB | |
| SCHEMBL30343473 | 0.64 | BCAT2 (0.53) | ALDH1A1KMT2AHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL1053659 | 0.64 | IKBKB (0.41) | ALDH1A1KMT2AMEN1HSD17B10TDP1 | |
| SCHEMBL5188338 | 0.64 | BCAT2 (0.53) | ALDH1A1KMT2AHSD17B10POLBSMN1; SMN2 | |
| SCHEMBL14980674 | 0.64 | MAPK8 (0.32) | ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |