Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 5/20 | 0.69 |
| ▸ | MMP8 | P22894 | 3/20 | 0.64 |
| ▸ | MMP9 | P14780 | 2/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.64 |
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.52 |
| ▸ | CPA1 | P15085 | 2/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201134 | 1.00 | FCER2 (0.69) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL12354885 | 0.90 | FCER2 (0.69) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL6021212 | 0.84 | CTSB (0.62) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL5552696 | 0.84 | CTSS (0.79) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL6020596 | 0.82 | CTSB (0.70) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL7353133 | 0.82 | FCER2 (0.57) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL7857865 | 0.82 | FCER2 (0.60) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL7353158 | 0.82 | FCER2 (0.57) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL6020170 | 0.82 | CTSS (0.58) | FCER2MMP8MMP9MMP2CTSB | |
| SCHEMBL7448015 | 0.82 | ALDH1A1 (0.68) | FCER2MMP8MMP9MMP2PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000930-A2 | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 2000-05-17 | — | — | EP | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1994004494-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |