Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MASP2 | O00187 | 1/20 | 0.30 |
| ▸ | GAPDH | P04406 | 1/20 | 0.30 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.30 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083136 | 0.77 | MAPT (0.39) | ALDH1A1MEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL7851192 | 0.74 | NFKB1 (0.39) | ALDH1A1CYP2C19MEN1POLBKMT2A | |
| SCHEMBL8693428 | 0.74 | NFKB1 (0.39) | ALDH1A1CYP2C19MEN1POLBKMT2A | |
| SCHEMBL7851194 | 0.74 | NFKB1 (0.39) | ALDH1A1CYP2C19MEN1POLBKMT2A | |
| SCHEMBL7851189 | 0.74 | NFKB1 (0.39) | ALDH1A1CYP2C19MEN1POLBKMT2A | |
| SCHEMBL8693432 | 0.74 | NFKB1 (0.39) | ALDH1A1CYP2C19MEN1POLBKMT2A | |
| SCHEMBL8084531 | 0.73 | ALDH1A1 (0.37) | ALDH1A1CYP2C19MEN1KMT2AL3MBTL1 | |
| SCHEMBL8089773 | 0.73 | — | — | |
| SCHEMBL8200316 | 0.70 | NR1H2 (0.37) | ALDH1A1MEN1POLBKMT2AGAA | |
| SCHEMBL8908962 | 0.68 | NFKB1 (0.36) | ALDH1A1CYP2C19MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | claimed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | claimed |
| EP-0770083-B1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 2000-08-30 | — | — | EP | disclosed |
| EP-0682030-B1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| EP-0647644-B1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| EP-0770083-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| WO-1996001829-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-25 | — | — | WO | disclosed |
| EP-0684244-A1 | 1,9-bridged thiazolo(3,2-a)quinoline derivatives | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| EP-0682030-A1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| EP-0647644-A1 | Antibacterial pyrido 1,2,3-d,e 1,3,4 benzoxacin derivatives | BAYER AG (DE) | 1995-04-12 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |