Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851192 | 0.92 | NFKB1 (0.39) | NFKB1NFKB2RELAALDH1A1MEN1 | |
| SCHEMBL8693432 | 0.92 | NFKB1 (0.39) | NFKB1NFKB2RELAALDH1A1MEN1 | |
| SCHEMBL7851194 | 0.92 | NFKB1 (0.39) | NFKB1NFKB2RELAALDH1A1MEN1 | |
| SCHEMBL8693428 | 0.92 | NFKB1 (0.39) | NFKB1NFKB2RELAALDH1A1MEN1 | |
| SCHEMBL7851189 | 0.92 | NFKB1 (0.39) | NFKB1NFKB2RELAALDH1A1MEN1 | |
| SCHEMBL8094739 | 0.92 | NFKB1 (0.40) | NFKB1NFKB2RELAMAOBMAOA | |
| SCHEMBL8907766 | 0.81 | ALDH1A1 (0.35) | NFKB1NFKB2RELAEPHX1ALDH1A1 | |
| SCHEMBL8092844 | 0.76 | JAK3 (0.39) | NFKB1NFKB2RELAEPHX1ALDH1A1 | |
| SCHEMBL8094774 | 0.75 | EPHX1 (0.36) | NFKB1NFKB2RELAMAOBMAOA | |
| SCHEMBL8097577 | 0.74 | CPB1 (0.47) | ALDH1A1MEN1TSHRKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770083-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001829-A1 | PYRIDO[3,2,1-i,j][3,1]BENZOXAZINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-25 | — | — | WO | disclosed |