Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656296 | 0.83 | ALDH1A1 (0.58) | PRMT1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL922778 | 0.83 | ALDH1A1 (0.58) | PRMT1ALDH1A1TSHRHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL1144014 | 0.82 | ALDH1A1 (0.56) | PRMT1ALDH1A1TSHRHSD17B10TDP1 | |
| Phosphoric Acid SCHEMBL11704340 | 0.78 | ALDH1A1 (0.51) | PRMT1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL16836836 | 0.75 | EPHX1 (0.48) | CYP19A1EPHX1MAOAMAOBANPEP | |
| SCHEMBL56025 | 0.75 | EPHX1 (0.48) | CYP19A1EPHX1MAOAMAOBANPEP | |
| SCHEMBL56469 | 0.75 | EPHX1 (0.48) | CYP19A1EPHX1MAOAMAOBANPEP | |
| SCHEMBL30537984 | 0.75 | EPHX1 (0.48) | CYP19A1EPHX1MAOAMAOBANPEP | |
| SCHEMBL9877652 | 0.74 | CA2 (0.42) | ALDH1A1POLBCA2HTR6ANPEP | |
| Sulfanilamide SCHEMBL8472428 | 0.74 | CA2 (0.63) | ALDH1A1TSHRHSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001927-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003823-A2 | NOVEL POLYAMINE ANALOGUES AS THERAPEUTIC AND DIAGNOSTIC AGENTS | ORIDIGM CORPORATION (US) | 1999-01-28 | — | — | WO | disclosed |