Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14330954 | 0.76 | MAPT (0.49) | CA2CYP4F2CYP4A11POLBALDH1A1 | |
| L-Phenylalaninol SCHEMBL8201376 | 0.74 | PRMT1 (0.44) | CA2POLBANPEPHTR6ALDH1A1 | |
| SCHEMBL922778 | 0.73 | ALDH1A1 (0.58) | CA2POLBHTR6ALDH1A1 | |
| SCHEMBL29656296 | 0.73 | ALDH1A1 (0.58) | CA2POLBHTR6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1144014 | 0.71 | ALDH1A1 (0.56) | CA2POLBHTR6ALDH1A1 | |
| SCHEMBL9162922 | 0.71 | CA2 (0.48) | CA2CYP4F2CYP4A11POLBHTR6 | |
| SCHEMBL9878796 | 0.70 | CA2 (0.41) | CA2ALDH1A1MAPK10 | |
| SCHEMBL3645517 | 0.69 | CA2 (0.47) | CA2POLBHTR6 | |
| SCHEMBL8257058 | 0.69 | KMT2A (0.51) | CA2ALDH1A1 | |
| SCHEMBL22615661 | 0.69 | PTGDR2 (0.49) | CA2PTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0171611-B1 | SUBSTITUTED PHENYLOXETHYL SULPHONES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |
| EP-0171611-A1 | Substituted phenyloxethyl sulphones and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-19 | — | — | EP | disclosed |