Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 13/20 | 0.96 |
| ▸ | PTGIR | P43119 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 2/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1288672 | 0.98 | NISCH (1.00) | NISCHPTGIRHTR1DADRA1ALMNA | |
| SCHEMBL8231902 | 0.88 | NISCH (0.74) | NISCHPTGIR | |
| SCHEMBL5476725 | 0.82 | NISCH (0.79) | NISCHHTR1DADRA1ALMNARECQL | |
| SCHEMBL8200536 | 0.82 | NISCH (0.71) | NISCHPTGIRADRA2AADRA2BADRA2C | |
| SCHEMBL8141372 | 0.77 | NISCH (1.00) | NISCHHTR1DADRA1ALMNARECQL | |
| SCHEMBL1886692 | 0.77 | NISCH (1.00) | NISCHHTR1DADRA1ALMNARECQL | |
| Hydrochloric Acid SCHEMBL7736746 | 0.76 | NISCH (0.62) | NISCHPTGIRRECQLTOP2ATOP2B | |
| SCHEMBL5807724 | 0.76 | PTGIR (1.00) | NISCHPTGIR | |
| SCHEMBL8197880 | 0.76 | NISCH (0.69) | NISCHHTR1DADRA1ALMNARECQL | |
| SCHEMBL8202670 | 0.76 | NISCH (0.69) | NISCHHTR1DADRA1ALMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |