Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18662207 | 0.80 | HRH1 (0.43) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL18662236 | 0.80 | HRH1 (0.43) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL1504701 | 0.80 | TSHR (0.46) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL6845944 | 0.78 | TSHR (0.39) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL5413664 | 0.78 | TAAR1 (0.52) | TAAR1TSHR | |
| SCHEMBL18662201 | 0.78 | HTR2A (0.41) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL18662240 | 0.78 | HTR2A (0.41) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL2101611 | 0.77 | TSHR (0.37) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL18662209 | 0.77 | HRH1 (0.40) | HTR2ATAAR1TSHRHRH1SLC6A3 | |
| SCHEMBL18662194 | 0.77 | HRH1 (0.40) | HTR2ATAAR1TSHRHRH1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022987-A | Aryl substituted alkylsilanes and a preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2000-02-08 | — | — | US | claimed |
| US-9862735-B2 | Organosilicon compound having diphenylethyl and methoxysilyl and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-20170088568-A1 | ORGANOSILICON COMPOUND HAVING DIPHENYLETHYL AND METHOXYSILYL AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-03-30 | — | — | US | disclosed |
| US-6022987-A | Aryl substituted alkylsilanes and a preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2000-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088568-A1 | ORGANOSILICON COMPOUND HAVING DIPHENYLETHYL AND METHOXYSILYL AND MAKING METHOD | MSN, SI, HDHD5 | HTR2A 2796/4885TAAR1 4505/4885TSHR 4488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.