SCHEMBL820183

SCHEMBL820183

CCCCC(C(=O)OCCC)[C@H](CC(=O)c1ccc(F)cc1)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
HTR7 P34969 1/20 0.43
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
POLB P06746 2/20 0.40
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
DRD2 P14416 4/20 0.37
DRD4 P21917 3/20 0.37
DRD3 P35462 3/20 0.37
TP53 P04637 1/20 0.37
CNR1 P21554 1/20 0.35
SLC6A3 Q01959 1/20 0.35
FAAH O00519 1/20 0.35
HTR1A P08908 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820203 0.94 HTR7 (0.48) L3MBTL1HTR7KMT2AMEN1LMNA
SCHEMBL820406 0.90 HTR7 (0.44) L3MBTL1HTR7POLBKMT2AMEN1
SCHEMBL820808 0.90 LMNA (0.42) L3MBTL1CYP2C9CYP2C19POLBKMT2A
SCHEMBL820185 0.90 PDPK1 (0.44) L3MBTL1CYP2C9CYP2C19POLBKMT2A
SCHEMBL820398 0.89 LMNA (0.43) L3MBTL1HTR7POLBKMT2AMEN1
SCHEMBL820191 0.89 HTR7 (0.45) L3MBTL1HTR7POLBKMT2AMEN1
SCHEMBL820403 0.88 HPGD (0.44) L3MBTL1HTR7CYP2C9CYP2C19POLB
SCHEMBL820811 0.84 HTR7 (0.40) L3MBTL1HTR7POLBKMT2AMEN1
SCHEMBL820405 0.83 KDM4E (0.42) HTR7POLBKMT2AMEN1LMNA
SCHEMBL820612 0.81 LMNA (0.47) L3MBTL1POLBKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222177-B2 Catalyst and reaction process JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2012-07-17 US disclosed
US-20110054190-A1 CATALYST AND REACTION PROCESS JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054190-A1 CATALYST AND REACTION PROCESS ME1, MAL2, ME2 L3MBTL1 2658/4885HTR7 1983/4885CYP2C9 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.