Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FHIT | P49789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452499 | 0.85 | CYP1A2 (0.55) | FHITALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL23827472 | 0.82 | FHIT (0.44) | FHITALDH1A1MAPTHPGDGAA | |
| SCHEMBL26784147 | 0.82 | ALDH1A1 (0.44) | FHITALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL10713707 | 0.81 | ALDH1A1 (0.41) | FHITALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL28298632 | 0.81 | MAPT (0.42) | FHITALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL9097179 | 0.80 | FHIT (0.72) | FHITALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8907220 | 0.80 | KDM4E (0.54) | FHITALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL3777716 | 0.80 | ALDH1A1 (0.67) | FHITALDH1A1MAPTHPGDGAA | |
| SCHEMBL133651 | 0.76 | ALDH1A1 (0.50) | FHITALDH1A1MAPTHPGDGAA | |
| Bromide SCHEMBL28146660 | 0.76 | FHIT (0.51) | FHITALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |