Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | FHIT | P49789 | 1/20 | 0.37 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713707 | 0.81 | ALDH1A1 (0.41) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL8201854 | 0.81 | FHIT (0.49) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL28357190 | 0.78 | GRIA2 (0.35) | — | |
| SCHEMBL3821809 | 0.77 | MAPT (0.42) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL28456462 | 0.77 | GPR35 (0.39) | ALDH1A1HPGDKDM4E | |
| SCHEMBL4794945 | 0.77 | ALDH1A1 (0.40) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL11039338 | 0.74 | CISD2 (0.37) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL2807538 | 0.74 | CISD2 (0.51) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL9291364 | 0.73 | LDHA (0.40) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL10713203 | 0.73 | ALDH1A1 (0.71) | MAPTRAB9AALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963858-A | N3The thieno uracil and application thereof that ring-type replaces | 拜耳股份公司 | 2019-07-02 | — | — | CN | disclosed |