Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28324973 | 0.82 | ALDH1A1 (0.70) | ALDH1A1LMNAL3MBTL1ATMTSHR | |
| SCHEMBL30059469 | 0.82 | L3MBTL1 (0.46) | ALDH1A1LMNAL3MBTL1HPGDCYP3A4 | |
| SCHEMBL3427031 | 0.82 | L3MBTL1 (0.46) | ALDH1A1LMNAL3MBTL1HPGDCYP3A4 | |
| SCHEMBL24074138 | 0.78 | GAA (0.41) | ALDH1A1LMNAL3MBTL1HPGDCYP3A4 | |
| SCHEMBL8208884 | 0.77 | L3MBTL1 (0.49) | ALDH1A1LMNAL3MBTL1HPGDCYP3A4 | |
| SCHEMBL16088748 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAHPGDTSHRMAPK8 | |
| SCHEMBL1262281 | 0.76 | L3MBTL1 (0.49) | ALDH1A1LMNAL3MBTL1HPGDCYP3A4 | |
| SCHEMBL29619558 | 0.76 | FOLH1 (0.55) | ALDH1A1L3MBTL1HPGDBCAT2TSHR | |
| SCHEMBL17875068 | 0.76 | LMNA (0.44) | ALDH1A1LMNAHPGDATMTSHR | |
| SCHEMBL2559743 | 0.76 | FOLH1 (0.55) | ALDH1A1L3MBTL1HPGDBCAT2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055068-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2008-05-08 | — | — | WO | disclosed |