Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 8/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 8/20 | 0.55 |
| ▸ | NPY4R | P50391 | 7/20 | 0.55 |
| ▸ | NPY1R | P25929 | 5/20 | 0.55 |
| ▸ | ERAP1 | Q9NZ08 | 6/20 | 0.52 |
| ▸ | NPY2R | P49146 | 4/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930562 | 0.90 | IL1RN (0.57) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL930564 | 0.90 | IL1RN (0.57) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL8203393 | 0.87 | NPY4R (0.47) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL8203303 | 0.83 | CAPN1 (0.62) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL28069215 | 0.73 | ERAP2 (0.60) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL28069213 | 0.73 | ERAP2 (0.60) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL30578432 | 0.72 | LNPEP (0.58) | ERAP2NPY4RNPY1RLNPEP | |
| SCHEMBL29275108 | 0.72 | IL1RN (0.59) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL29275103 | 0.72 | IL1RN (0.59) | IL1RNERAP2NPY4RNPY1RERAP1 | |
| SCHEMBL9073868 | 0.72 | OPRK1 (0.65) | NPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048121-A2 | MACROCYCLIC CYSTEINE PROTEASE INHIBITORS AND COMPOSITIONS THEREOF | LINCOLN UNIVERSITY (NZ) | 2008-04-24 | — | — | WO | disclosed |