Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 6/20 | 0.47 |
| ▸ | NPY1R | P25929 | 4/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 9/20 | 0.47 |
| ▸ | IL1RN | P18510 | 8/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202889 | 0.87 | IL1RN (0.55) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL930564 | 0.81 | IL1RN (0.57) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL930562 | 0.81 | IL1RN (0.57) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL8203303 | 0.75 | CAPN1 (0.62) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL15275801 | 0.71 | TAS1R3 (0.50) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL28069215 | 0.69 | ERAP2 (0.60) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL27431221 | 0.69 | ERAP2 (0.62) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL28069213 | 0.69 | ERAP2 (0.60) | NPY4RNPY1RERAP2IL1RNERAP1 | |
| SCHEMBL30578432 | 0.68 | LNPEP (0.58) | NPY4RNPY1RERAP2LNPEP | |
| SCHEMBL12864511 | 0.68 | TSHR (0.68) | NPY4RNPY1RERAP2IL1RNERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048121-A2 | MACROCYCLIC CYSTEINE PROTEASE INHIBITORS AND COMPOSITIONS THEREOF | LINCOLN UNIVERSITY (NZ) | 2008-04-24 | — | — | WO | disclosed |