Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.54 |
| ▸ | F12 | P00748 | 2/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342778 | 0.84 | HSPD1 (0.55) | HSPD1HSPE1CFTRF12KMT2A | |
| SCHEMBL5241258 | 0.82 | ITK (0.54) | CFTRNTRK1KMT2AMEN1TDP1 | |
| SCHEMBL31265782 | 0.80 | PKM (0.61) | HSPD1HSPE1KMT2AMEN1ALDH1A1 | |
| SCHEMBL15850171 | 0.76 | ITK (0.67) | CFTRKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL4725368 | 0.75 | DYRK1A (0.60) | KDRALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL9967909 | 0.74 | HSPD1 (0.67) | HSPD1HSPE1F12KMT2AMEN1 | |
| SCHEMBL3368022 | 0.74 | TYK2 (0.70) | CFTRKMT2AMEN1TDP1ALDH1A1 | |
| SCHEMBL15837010 | 0.73 | ERCC1 (0.53) | KDRKMT2AALDH1A1MAOAMAOB | |
| SCHEMBL23825504 | 0.73 | SORT1 (0.74) | HSPD1HSPE1F12ALDH1A1 | |
| SCHEMBL29980628 | 0.73 | SORT1 (0.74) | HSPD1HSPE1F12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021725-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |