Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL719839 | 0.84 | POLB (0.33) | POLB | |
| Hydrochloric Acid SCHEMBL818807 | 0.83 | SLC25A5 (0.32) | — | |
| Fluoride Ion SCHEMBL7643026 | 0.81 | POLB (0.33) | POLB | |
| Hydrochloric Acid SCHEMBL818263 | 0.81 | ALDH1A1 (0.32) | POLB | |
| Hydrochloric Acid SCHEMBL820388 | 0.81 | — | — | |
| SCHEMBL8390465 | 0.80 | POLB (0.32) | POLB | |
| Hydrochloric Acid SCHEMBL7918194 | 0.80 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL818847 | 0.78 | MEN1 (0.31) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL5081115 | 0.77 | MAPT (0.39) | — | |
| Hydrochloric Acid SCHEMBL7913319 | 0.77 | MEN1 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982236-B2 | Process to polymerize olefins | UNIVATION TECHNOLOGIES, LLC (US) | 2006-01-03 | — | — | US | claimed |
| US-6897273-B2 | Catalyst composition, method of polymerization and polymer therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2005-05-24 | — | — | US | claimed |
| EP-1392743-A2 | CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM | Univation Technologies LLC (US) | 2004-03-03 | — | — | EP | claimed |
| US-20040039138-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2004-02-26 | — | — | US | claimed |
| US-6656866-B2 | Metallocene and non-metallocene, homogeneous catalysts, particularly for use in the economical gas and slurry phase processes; spray dried olefin polymerization catalysts | UNIVATION TECHNOLOGIES, LLC | 2003-12-02 | — | — | US | claimed |
| US-20030207762-A9 | CATALYST PREPARATION METHOD | UNIVATION TECHNOLOGIES, LLC | 2003-11-06 | — | — | US | claimed |
| US-6620894-B2 | Calibration; using coordination catalyst | UNIVATION TECHNOLOGIES, LLC | 2003-09-16 | — | — | US | claimed |
| US-20020132937-A1 | Start-up procedure for multiple catalyst polymerization systems | UNIVATION TECHNOLOGIES, LLC | 2002-09-19 | — | — | US | claimed |
| US-20020119890-A1 | Catalyst preparation method | WENZEL TIMOTHY T (US) | 2002-08-29 | — | — | US | claimed |
| US-20020103310-A1 | Catalyst composition, method of polymerization and polymer therefrom | UNIVATION TECHNOLOGIES, LLC | 2002-08-01 | — | — | US | claimed |
| WO-2002046250-A2 | CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2002-06-13 | — | — | WO | claimed |
| US-20240343840-A1 | PROCESS FOR PRODUCING POLYOLEFIN GRANULAR RESIN WITH INCREASED SETTLED BULK DENSITY | W.R. GRACE & CO.-CONN. (US) | 2024-10-17 | — | — | US | disclosed |
| US-20220324895-A1 | DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER | UNIV NEW YORK (US) | 2022-10-13 | — | — | US | disclosed |
| US-9416069-B2 | Scalable production of precision hydrocarbons from trialkylaluminum via ternary living coordinative chain transfer polymerization | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2016-08-16 | — | — | US | disclosed |
| US-9175103-B2 | Living coordinative chain transfer polymerization with dynamic counterion exchange | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2015-11-03 | — | — | US | disclosed |
| EP-0811637-A2 | Method for feeding a liquid catalyst to a fluidized bed polmerization reactor | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-10 | — | — | EP | disclosed |
| US-5693727-A | INTRODUCING MONOMERS INTO POLYMERIZATION ZONE CONTAINING BED OF GROWING POLYMER PARTICLES, INTRODUCING UNSUPPORTED POLYMERIZATION CATALYST IN LIQUID FORM INTO VESSEL, WITHDRAWING POLYMERIC PRODUCT, UNREACTED MONOMERS, GASES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |
| US-5672669-A | CONTACTING ETHYLENE WITH A SPRAY DRIED METALLOCENE CATALYST AND A COCATALYST CAPABLE OF ACTIVATING THE CATALYST, AND AN INERT FILLER PARTICLES, HOMO OR COPOLYMERIZATION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |
| US-5648310-A | Spray dried, filled metallocene catalyst composition for use in polyolefin manufacture | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0668295-A1 | Spray dried, filled metallocene catalyst composition for use in polyolefin manufacture | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324895-A1 | DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER | ALG1, PPOX, MANBA | MEN1 3774/4885POLB 126/4885KMT2A 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.