Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126546 | 0.84 | HPGD (0.64) | HPGDMAPK1RAB9ANPC1L3MBTL1 | |
| SCHEMBL8202821 | 0.83 | LMNA (0.44) | HPGDMAPK1NPSR1RAB9ANPC1 | |
| SCHEMBL15151364 | 0.78 | MAPK1 (0.45) | HPGDMAPK1RAB9ANPC1L3MBTL1 | |
| SCHEMBL22137307 | 0.74 | MAPK1 (0.52) | HPGDMAPK1NPSR1RAB9ANPC1 | |
| SCHEMBL7256405 | 0.73 | NPSR1 (0.79) | HPGDMAPK1NPSR1RAB9ANPC1 | |
| SCHEMBL26088689 | 0.73 | MAPK1 (0.61) | HPGDMAPK1RAB9ANPC1L3MBTL1 | |
| SCHEMBL10618518 | 0.71 | MAPK1 (0.75) | HPGDMAPK1RAB9ANPC1L3MBTL1 | |
| SCHEMBL17520292 | 0.70 | NPSR1 (0.49) | HPGDMAPK1NPSR1RAB9ANPC1 | |
| SCHEMBL26422717 | 0.69 | NPSR1 (0.59) | HPGDMAPK1NPSR1RAB9ANPC1 | |
| SCHEMBL15151658 | 0.68 | RAB9A (0.49) | HPGDMAPK1NPSR1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591355-B1 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY | CYTOPHARM INC (US) | 2000-03-08 | — | — | EP | disclosed |
| EP-0591355-A4 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY. | CYTOPHARM INC (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0591355-A1 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY | CYTOPHARM, INC. (US) | 1994-04-13 | — | — | EP | disclosed |
| US-5262401-A | Porphyrins as antitumor agents and psoriasis treatment | CYTOPHARM, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5179120-A | Antitumor agents or psoriasis | CYTOPHARM, INC. (US) | 1993-01-12 | — | — | US | disclosed |
| WO-1993000087-A1 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY | CYTOPHARM, INC. (US) | 1993-01-07 | — | — | WO | disclosed |