Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 9/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KIF5B | P33176 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982589 | 0.84 | CSF1R (0.57) | CSF1RPDGFRBFLT4FLT3SAE1 | |
| SCHEMBL7455646 | 0.82 | CSF1R (0.59) | CSF1RPDGFRBFLT4FLT3EGFR | |
| SCHEMBL7962833 | 0.75 | TRPA1 (0.52) | CSF1RPDGFRBFLT4FLT3TRPA1 | |
| SCHEMBL13618122 | 0.70 | MAOB (0.54) | — | |
| SCHEMBL4359665 | 0.69 | CSF1R (0.81) | CSF1RPDGFRBFLT4FLT3EGFR | |
| SCHEMBL2329011 | 0.68 | CYP3A4 (0.49) | PDGFRBKITPDGFRA | |
| SCHEMBL7455398 | 0.67 | PDGFRB (0.64) | CSF1RPDGFRBFLT4FLT3EGFR | |
| SCHEMBL15607578 | 0.67 | PDGFRB (0.77) | CSF1RPDGFRBFLT4FLT3EGFR | |
| SCHEMBL18864590 | 0.67 | MAOB (0.51) | PDGFRBPDGFRA | |
| SCHEMBL30522847 | 0.67 | MAOB (0.51) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071921-A | Chemical compounds | ZENECA LIMITED (GB) | 2000-06-06 | — | — | US | disclosed |