Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.80 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.80 |
| ▸ | PGR | P06401 | 6/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 2/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | AR | P10275 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524485 | 0.91 | LMNA (0.83) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL14114135 | 0.91 | LMNA (0.83) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL11864138 | 0.91 | LMNA (0.72) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL124165 | 0.90 | HIF1A (0.87) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL11422147 | 0.90 | HIF1A (0.87) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL28971361 | 0.90 | HIF1A (0.87) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL15975096 | 0.90 | HIF1A (0.87) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL14884636 | 0.90 | HIF1A (0.87) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL13985471 | 0.90 | LMNA (0.81) | LMNAHIF1ACYP3A4NR3C1PGR | |
| SCHEMBL1973547 | 0.90 | HIF1A (0.81) | LMNAHIF1ACYP3A4NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059237-A2 | NOVEL GLUCOCORTICOID RECEPTOR AGONISTS AND IMMUNOCONJUGATES THEREOF | ADCENTRX THERAPEUTICS INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| US-20210252159-A1 | CONJUGATES OF CARTILAGE-HOMING PEPTIDES | FRED HUTCHINSON CANCER CENTER | 2021-08-19 | — | — | US | disclosed |
| EP-0876393-B1 | 21-(2-OXO-TETRAHYDROFURAN)-THIO PREGNANE DERIVATIVES, A PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LTD (GB) | 2000-07-05 | — | — | EP | disclosed |
| US-6013244-A | AS ANTI-INFLAMMATORY OR ANTI-ALLERGIC AGENTS | GLAXO WELLCOME INC. (US) | 2000-01-11 | — | — | US | disclosed |
| US-3975378-A | ANTIINFLAMMATORY | SYNTEX (U.S.A.) INC. (US) | 1976-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210252159-A1 | CONJUGATES OF CARTILAGE-HOMING PEPTIDES | CD44, MATR3, CCL2 | LMNA 2456/4885HIF1A 1623/4885CYP3A4 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.