SCHEMBL820469

SCHEMBL820469

CC(=O)O/C=C/C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820470 1.00 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL654628 0.79
SCHEMBL19386388 0.77 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL667159 0.77
SCHEMBL28814140 0.77 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL11548991 0.75
SCHEMBL11548988 0.75
SCHEMBL515760 0.74 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL15034490 0.74 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL515761 0.74 ALDH1A1 (0.44) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1930310-B1 PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONALDEHYDE CENTRAL GLASS CO LTD (JP) 2011-11-16 EP disclosed
US-20110263941-A1 ENDOSCOPE DESIGNS AND METHODS OF MANUFACTURE Intergrated Endoscopy,Inc. (US) 2011-10-27 US disclosed
EP-1950191-B1 PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONIC ACID CENTRAL GLASS CO LTD (JP) 2011-10-19 EP disclosed
US-7880033-B2 hydrolyzing benzyl vinyl ether derivative in presence of an acid catalyst Lewis acid or H2SO4 thereby obtaining 3,3,3-trifluoropropionaldehy, oxidizing intermediate with HNO3 to produce 3,3,3-triluoropropionic acid; cost efficiency CENTRAL GLASS COMPANY, LIMITED (JP) 2011-02-01 US disclosed
US-20090247786-A1 Process For Producing 3,3,3-Trifluoropropionic Acid CENTRAL GLASS COMPANY, LIMITED (JP) 2009-10-01 US disclosed
US-7544844-B2 Process for producing 3,3,3-trifluoropropionaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2009-06-09 US disclosed
US-20090105506-A1 Process for Producing 3,3,3-Trifluoropropionaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2009-04-23 US disclosed
EP-1950191-A1 PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONIC ACID Central Glass Co., Ltd. (JP) 2008-07-30 EP disclosed
EP-1930310-A1 PROCESS FOR PRODUCING 3,3,3-TRIFLUOROPROPIONALDEHYDE Central Glass Co., Ltd. (JP) 2008-06-11 EP disclosed
WO-1998058892-A2 PREPARATION OF FLUOROALKYL COMPOUNDS AND THEIR DERIVATIVES ALLIEDSIGNAL INC. (US) 1998-12-30 WO disclosed
US-5777184-A Preparation of fluoroalkyl compounds and their derivatives ALLIEDSIGNAL INC. (US) 1998-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247786-A1 Process For Producing 3,3,3-Trifluoropropionic Acid HAO2, ALDH1A3, AOX1 ALDH1A1 14/4885TSHR 1586/4885
US-20090105506-A1 Process for Producing 3,3,3-Trifluoropropionaldehyde ALDH1A3, ALDH7A1, ALDH1A1 ALDH1A1 3/4885TSHR 636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.