Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204827 | 0.79 | CA2 (0.50) | CA2CYP19A1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL8199657 | 0.79 | CHRNB4 (0.54) | CA2ADRA1DADRA1AADRA1BCHRNB4 | |
| SCHEMBL13998649 | 0.76 | ADRA1D (0.50) | CYP19A1ADRA1DADRA1AADRA1BMAPK1 | |
| SCHEMBL8125243 | 0.76 | CA2 (0.58) | CA2CYP19A1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL1044198 | 0.75 | PARP1 (0.33) | — | |
| SCHEMBL7218131 | 0.75 | CA2 (0.47) | CA2CYP19A1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL1519103 | 0.73 | CA2 (0.49) | CA2CYP19A1L3MBTL1CYP11B1CYP11B2 | |
| SCHEMBL7216342 | 0.73 | CA2 (0.52) | CA2L3MBTL1CYP11B1CYP11B2MAPK1 | |
| SCHEMBL30499165 | 0.73 | CA2 (0.41) | CA2CYP19A1L3MBTL1ADRA1DADRA1A | |
| SCHEMBL266615 | 0.72 | NISCH (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058301-A1 | N-[2-(4-AMINOPHYL)ETHYL]-2,3-DIHYDRO-1,4-BENZODIOXINE-2-METHANAMINE, PRODUCTION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2000-10-05 | — | — | WO | disclosed |