Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206526 | 0.79 | TACR1 (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5995515 | 0.74 | HTR3A (0.42) | SIGMAR1HTR3AADRB1HTR3EHTR3B | |
| SCHEMBL7346729 | 0.70 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL654167 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL592479 | 0.68 | SIGMAR1 (0.67) | SIGMAR1HTR3AADRB1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL7034100 | 0.68 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL5595516 | 0.68 | CHRM2 (0.57) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4464240 | 0.67 | SIGMAR1 (0.65) | SIGMAR1HTR3AADRB1HTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL6290497 | 0.67 | SIGMAR1 (0.65) | SIGMAR1HTR3AADRB1HTR3EHTR3B | |
| SCHEMBL8205876 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973780-A1 | ANTIBACTERIAL SUBSTITUTED 7-ACYLAMINO -3-(METHYLHYDRAZONO) METHYL-CEPHALOSPORINS AND INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043981-A1 | ANTIBACTERIAL SUBSTITUTED 7-ACYLAMINO-3-(METHYLHYDRAZONO)METHYL -CEPHALOSPORINS AND INTERMEDIATES | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1998-10-08 | — | — | WO | disclosed |